Modifications of Antibodies
Antibody Conjugation
Conjugation of your antibody to enzymes and dyes.
Antigen Conjugation
Conjugation of your antigen to carriers for better immune response.
Antibody Fragmentation
F(ab) and F(ab)2 fragmentation of your antibodies.
Order Process
Antibody Conjugation
Antibody conjugations adapted to your specific requirements. The modifications are available for antibodies that you provide us and that Davids creates for you. Table 1 summarizes the most common modifications for antibodies. If you require different antibody conjugations, please contact us at info@davids-bio.com.
Dye Conjugation | Enzyme Conjugation | Protein Conjugation | Liposome Introduction | |
---|---|---|---|---|
Cat.No. | P801 (FITC) P802 (RhodaminB) | P804 (AP) P805 (HRP) | P803 (Biotin) | P808 |
Available for | IgY, IgG, IgM | IgY, IgG, IgM | IgY, IgG, IgM | Proteins |
Amount | Up to 5 mg | Up to 2 mg (P804) Up to 5 mg (P805) | Up to 5 mg | |
Conjugation with | FITC RhodaminB More on request | Alkaline Phosphatase Horse Radish Peroxidase More on request | Biotin More on request | Inclusion in liposomes |
Price | Price List | Price List | Price List | Price on demand |
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Antigen Conjugation
Antigen conjugation can improve immune response, particularly for antigens with low antigenicity. Small antigens, such as peptides, haptenes, or medicines, can become larger by forming multimers, resulting in a stronger immune response in the majority of situations. For proteins less than 15 kDa, that will be used for immunizations, we propose conjugation to a carrier such as KLH, BSA, Ovalbumin, or Thyroglobulin. Furthermore, a modification for hazardous antigens may be required to minimize toxicity prior to vaccination. Please see our Antigen Page for further information on antigen requirements, or our Peptide Antibody Page for peptide conjugations.
Antibody-Fragmentation
F(ab)-Fragmentation | F(ab)2-Fragmentation | F(ab)2-Fragmentation Chicken | |
---|---|---|---|
Cat.No. | P901 | P902 | P903 |
Available for | IgG | IgG | IgY |
Species | Mammalian | Mammalian | Birds |
Amount | 1 - 10 mg IgG | 1 - 10 mg IgG | 1 - 10 mg IgY |
Enzyme | Papain | Pepsin | Pepsin |
Fragmentation (approx.) | 55 kDa F(ab) | 110 kDa F(ab)2 | 110 kDa F(ab)2 |
Price | Price List | Price List | Price List |
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Order Process
Simply ask for the desired modification by email for antibodies and antigens made by Davids. We recommend contacting us before modifying antibodies or antigens from your own lab because each alteration is unique. You can email your material to be modified to:
Davids Biotechnologie GmbH
Roentgenstrasse 3
93055 Regensburg
Germany
- Your Material for Modification
- Concentration & Buffer Conditions of your material
- Our Offer, our order form or your official PO
- VAT number (only EU customers, not required by German customers)
If you want to order one of our antibody services visit our Antibody Services Overview.